Case Study: Delivering Early Enrollment Against Aggressive Timelines in a Phase II Parkinson’s Disease Study
How a Site-Centric Delivery Model Accelerated Study Start-Up
When a Phase II Parkinson’s disease study faced aggressive start-up and enrollment targets, the study team was tasked with achieving first patient consent within just eight weeks of final protocol release. The trial’s hybrid design, incorporating both in-clinic and at-home treatment, combined with the challenges of recruiting patients experiencing fluctuating OFF episodes, created significant operational complexity and timeline pressure.
This case study demonstrates how a focused operational strategy, leveraging accelerated start-up execution, targeted site selection, proactive patient identification, and close coordination across stakeholders, helped drive early recruitment momentum and exceed sponsor enrollment milestones despite protocol changes and evolving study demands.
Download the full case study to learn how strategic site engagement, operational agility, and specialized neurology trial expertise can accelerate study start-up and support successful delivery in complex Parkinson’s disease clinical research programs.
Related resources
Poster Presentation: GRIPonMASH Preliminary Results
Comparing FIB-4 and MAF-5 for Advanced Fibrosis Screening in Primary Care Complete the form to access the poster and explore the preliminary GRIPonMASH findings.[gravityform id="19" title="false"]As the prevalence of MASLD and MASH contin...
Fact Sheet: A Science-Led Partner for Alzheimer’s Disease Clinical Development
Alzheimer's Disease CRO Expertise for Complex Clinical Trials As Alzheimer's research shifts toward earlier intervention and biomarker-defined populations, sponsors need more than operational support. They need a partner who understands the scien...
Peer Reviewed Publication: Evaluating Gender Representation in Alzheimer’s Disease Trial Eligibility Criteria
Ensuring that Alzheimer’s disease (AD) clinical trials reflect real-world patient populations remains a key challenge, as eligibility criteria can unintentionally influence who is able to participate. A recent study published in The Journal of P...